Amoxycillin is considered the drug of choice for the treatment of acute sinusitis, acute otitis media, and of acute exacerbations of chronic bronchitis. In these cases it is superior to ordinary penicillin. It is also suitable for the treatment of streptococcal pharyngitis (e.g. in children). Amoxycillin is also important as an alternative to co-trimoxazol for uncomplicated infections of the urinary tract (possibly as a single dose for non-pregnant women).

According to provisional studies, amoxycillin in high doses (minimum 2 g/day for two weeks in combinbation with e.g. omeprazole) is suitable for the eradication of Helicobacter pylori (prevention of ulcer recurrence).

Amoxycillin can also be administered for other infections (e.g. Lyme disease, systemic salmonellosis, meningitis, gonorrhoea) for which, however, it is not considered the drug of choice. Amoxycillin (possibly in combination with an aminoglycoside) is the substance of choice for the prevention of endocarditis during interventions in the oropharynx, urogenital and gastrointestinal tracts.

The combination with clavulanic acid is suitable for the treatment of infections with Staph. aureus, with Bacteroides fragilis, or with b-lactamase producing H. influenzae and E. coli.

Table of Contents | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | Risk Groups | References