Amoxycillin hinders the cell wall synthesis of sensitive bacteria and is bactericidal. It is active against all penicillin-sensitive bacteria: streptococci and most strains of pneumococci, gonococci, and meningococci are sensitive. Bacteria that produce ß-lactamase (e.g. most of the staphylococci) are resistant. Amoxycillin is also active against strains of haemophilus influenza that do not produce ß-lactamase, against Branhamella catarrhalis, and partially against E. coli, Proteus mirabilis and salmonella. In combination with the ß-lactamase inhibitor clavulanic acid it is effective against ß-lactamase producing staphylococci, H. influenzae, and Bacteroides fragilis.

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