In comparison with propranolol, atenolol has a selective effect on ß1-receptors and it can therefore be considered (relatively) cardioselective. It does not have intrinsic sympathomimetic effects. Atenolol reduces both submaximal and maximal exercise heart rates and delays atrioventricular conduction. The betablockade also leads to a certain reduction of contractility. On the whole the oxygen requirements decrease. Atenolol can lead to a reduction of peripheral blood flow and to an increase of plasma triglycerides and total cholesterol as well as to reduced high-density lipoprotein cholesterol values.

Table of Contents | Indications | Adverse Reactions & Interactions | Contraindications & Cautions | Risk Groups | References