Atenolol Tables:

Pharmacokinetics

Bioavailability Peak plasma level Plasma half-life Active metabolites Elimination
little variability 45-55% 2 to 4 hours 6 to 8 hours* none renal
*The duration of the effects is 24 hours.

Dose
Indication Administration
Initial loading dose
Dose Interval
Maintenance dose
Dose Interval
hypertension/angina pectoris/status after infarction oral 25-50 mg 24 hours 25-100 mg 24 hours
cardiac emergencies i.v. 2.5-5 mg 15 minutes* - -
*Only one repetition allowed (highest total dose 10 mg); then oral administration.

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