Pregnant women: Can be given during the first two trimesters. Non-steroidal anti-inflammatory agents should be avoided in the third trimester.

Nursing mothers: Allowed in small doses. Only minimal amounts were detected in breast milk.

Children: Daily dose: 1-3 mg/kg divided into two or three doses. Avoid in children younger than one year (not enough documentation).

Elderly people: Generally dose adjustment is not necessary. Anti-inflammatory agents cause more side-effects in the elderly.

Renal failure: No dose adjustment necessary.

Liver insufficiency: Despite predominantly hepatic elimination a dose adjustment is not necessary.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References