Pregnant women: Can be administered.

Nursing mothers: Can be administered.

Children: 0 to 10 years of age: initially 0.025 mg/kg, could be repeated after six hours. Maintenance dose 0.01 mg/kg/24 hrs. Older children same as adults.

Elderly people: Even when the plasma-creatinine values are normal the renal functions can be limited! Small doses.

Renal failure: Scheme for the adjustment of the doses: plasma-creatinine 110-220 µmol/l: reduction of the maintenance dose by 1/3. plasma-creatinine 220-700 µmol/l: reduction of the maintenance dose by 1/2. plasma-creatinine over 700 µmol/l: reduction of the maintenance dose by 2/3 to 3/4.

Liver insufficiency: No particular problems.

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