Doxycycline acts bacteriostatically by binding with ribosomes and thus inhibiting the bacterial protein synthesis. In high doses it is also detrimental to the protein synthesis in human cells. Like other tetracyclines, doxycycline is a broad spectrum antibiotic and it is active against a very large number of microorganisms. Some important examples are: many strains of Staphylococcus aurea, E. coli, Roteus mirabilis, Klebsiella, many anaerobes, many strains of Haemophilus influenzae, Brucella, Vibrio cholerae, chlamydias, mycoplasms, rickettsiae, treponemas, borellias, amebas, and partially Plasmodium falciparum.

Table of Contents | Indications | Adverse Reactions & Interactions | Contraindications & Cautions | Risk Groups | References