Here are some of the few side-effects that hydroxocobalamin causes: diarrhea, exanthema, pruritus, urticaria, pain at the site of injection.

At the beginning of the treatment of a severe pernicious anemia, a hypokalemia may occur due to the increased potassium requirements for the maturation of the red cells.

American literature reports the possibility of the formation of antibodies against the hydroxocobalamin-transcobalamin-II complex.

Hydroxocobalamin: Interactions

Nitrous oxydes (N₂O) can chemically inactivate cobalamins; this can be significant if the patient with pernicious anemia undergoes repeated anesthesias.

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