Hydroxyzine Tables:
Pharmacokinetics
Bioavailability
Peak plasma level
Plasma half-life
Active metabolites
Elimination
constant
not established
2 hours
15 to 30 hours
important*
partially extrarenal
*
Cetirizine
, the most important metabolite, has a half-life of approximately 8 hours and is excreted unaltered predominantly through the kidneys.
Dose
Indication
Administration
Initial loading dose
Dose
Interval
Maintenance dose
Dose
Interval
pruritus
oral
12.5-25 mg
12 to 24 hours*
12.5-50 mg
12 to 24 hours
*Administration is best in the evening; maybe a small dose during the day. Observe individual sensitivities!
Copyright © 1996 Infomed-Verlags AG