Pregnant women: A connection to malformations is suspected but not proven. Avoid if possible in the first trimester.

Nursing mothers: Imipramine is eliminated in breast milk: better avoided!

Children: Do not use before 6 years of age. Initially 10-25 mg in the evenings for enuresis. Daily doses exceeding 3.5 mg/kg only allowed when there is close monitoring. Accidental taking of several tablets is life threatening in young children!

Elderly people: Particularly cautious dosage (dangers: orthostatic hypotension, retention of urine, confusion): begin with 50% of the usual adult dose.

Renal failure: No dose adjustment is necessary.

Liver insufficiency: Individual dose reduction is recommended.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References