Pregnant women: Not generally contraindicated during pregnancy; however, there are no studies involving humans.

Nursing mothers: No adequate studies are available.

Children: Hardly used; no adeqaute studies available.

Elderly people: Mind the danger of hypotension at the beginning of treatment: low dosage!

Renal failure: No dose adjustment necessary.

Liver insufficiency: Increased bioavailability when there is cirrhosis of the liver. Necessity of a dose reduction is not clear.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References