Lactulose Tables:
Pharmacokinetics
Bioavailability
onset of action
Elimination
little absorption of lactulose occurs
24 to 48 hours
very small amounts in urine and stool
Dose
Indication
Administration
Initial loading dose
Dose
Interval
Maintenance dose
Dose
Interval
constipation
oral
10-20 g (15-30 ml)
24 hours
10-30 g(15-45 ml)
24 hours
portal-systemic encephalopathy
oral
20-30 g (30-45 ml)
8 hours
10-30 g(15-45 ml)*
8 to 24 hours*
*Adjust dose individually so that the patients have two to three stools per day.
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