Pregnant women: High doses cause malformations in animal experiments. Better avoided!

Nursing mothers: Inhibits lactation and is probably excreted through breast milk: avoid if possible!

Children: Only very limited experiences. Indication and tolerance are not positively established.

Elderly people: Very cautious dosage (increased risk of psychiatric and cardiovascular problems). Initial treatment and major readjustments may have to be performed in the hospital.

Renal failure: No dose adjustment necessary.

Liver insufficiency: Poor documentation. Has been used for hepatic coma in isolated cases.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References