Pregnant women: No known teratogenic effects. Allowed when indications are unambiguous.

Nursing mothers: Higher concentrations in breast milk than in plasma! Nevertheless, most specialists consider a metoclopramide therapy compatible with breast-feeding.

Children: Extrapyramidal movement disorders are particularly frequent. Avoid if possible!

Elderly people: Increased risk of tardive dyskinesias. Avoid long-term administration.

Renal failure: Dose reduction is indicated (50% for advanced failure).

Liver insufficiency: 50% dose reduction when there is advanced insufficiency.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References