Metronidazole, a synthetic 5-nitroimidazole, has an antibiotic action that is based on the modification of the genetic substance of microorganisms. Its spectrum contains anaerobic bacteria (Bacteroides fragilis, clostridia, fusobacteria, peptococci, peptostreptococci), certain other bacteria (e.g. Gardnerella vaginalis) and protozoas (Giardia lamblia, Entameba hystolytica, Trichomonas vaginalis). Bactericidal tissue concentrations are achieved in the central nervous system, in the liver and the bile ducts, in the bones, in vaginal secretions, and in the pelvic organs.

Table of Contents | Indications | Adverse Reactions & Interactions | Contraindications & Cautions | Risk Groups | References