Pregnant women: Even though a correlation between benzodiazepines and malformations is not safely established, midazolam should be avoided if possible.

Nursing mothers: Midazolam is eliminated through breast milk: better avoided.

Children: Usual parenteral single dose: 0.08 to 0.15 mg/kg (maximum of 0.20 mg/kg). 0.35 to 0.45 mg/kg can be given rectally.

Elderly people: Greatest care is indicated in the elderly (and when general condition is impaired): initially no more than 50% of the usual dose!

Renal failure: Dose reduction may be indicated (individual adjustment).

Liver insufficiency: Dose reduction may be indicated (individual adjustment).

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References