Pregnant women: Can be given if indication is unambiguous. Risks for the child: malformations (?), inhibition of intra-uterine growth, suppression of the adrenal cortex or the immune defense.

Nursing mothers: Can be given. Concentrations in breast milk are relatively low. Following single doses of more than 20 mg: no nursing for 4 hours.

Children: Increased risks (obesity, growth retardation): avoid long-term administration if possible! Acute therapy: 1 to 2 mg/kg/day.

Elderly people: Low dosage, mind the risk of osteoporosis!

Renal failure: Plasma levels may be increased: some specialists recommend a dose reduction, others do not consider it necessary.

Liver insufficiency: Significantly increased plasma levels if there is advanced insufficiency; dose may have to be reduced.

Table of Contents | Indications | Pharmacology | Adverse Reactions & Interactions | Contraindications & Cautions | References