Salbutamol has a pronounced bronchodilatatory effect on all forms and degrees of severity of bronchial asthma. It is therefore very well suited for the acute treatment of bronchospasms, even if the attacks are severe. Fenoterol and terbutaline have a similar effect, whereas formoterol and salmeterol have longer lasting effects. Correct use is important for a successful treatment. If someone has problems with a metered dose aerosol, he or she may achieve better results with an inhalation aid (spacers) or with a powder inhaler. More side-effects occur following oral administration. Inhalation with a nebulizer or parenteral administration are only indicated if the asthma attacks are severe. If there are reversible alterations, salbutamol could also be of use for chronic obstructive pulmonary disease.

According to many specialists, beta-sympathomimetic drugs are not suited for long-term treatment because of the potential side-effects. Anti-inflammatory agents (especially inhaled corticosteroids) are the drugs recommended for the primary therapy of bronchial asthma.

Salbutamol can also be used in infusions for the prevention of premature labour at the end of pregnancy and for the therapy of hyperkalemia.

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