Salbutamol: Pharmacology

Salbutamol (albutrerol in the USA) is a selective B2-adrenoceptor stimulant that causes the relaxation of the smooth muscles through the increase of the intracellular cyclic adenosine monophosphate (cAMP): bronchial and uterine muscles are relaxed, the peripheral vessels are dilated, heart rate increases, and there are metabolic effects (e.g. decrease of the plasma potassium levels). Salbutamol also has certain anti-inflammatory properties whose clinical significance is not determined.

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