Salbutamol Tables:

Pharmacokinetics

Bioavailability Peak plasma level Plasma half-life Active metabolites Elimination
almost constant 50%* 2 to 3 hours 3 to 5 hours none partially renal
*Through inhalation, 10% to a maximum of 20% of a dose are available in the airways.

Dose
Indication Administration
Initial loading dose
Dose Interval
Maintenance dose
Dose Interval
bronchial asthma with metered dose aerosol* 100-200 µg (1 to 2 puffs)* 4 hours (avoid long-term treatment) -
*The dose administered with the metered dose aerosol can exceptionally be increased to 300 to 400 µg (after 5 minutes). 400 µg/dose are normally administered with the powder inhaler. When administered with the nebulizer 1.25 mg in 2-3 ml of a sodium chloride solution are inhaled for 15 minutes.

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